- An epoxy-functional silane: 3-Glycidyloxypropyltrimethoxysilane, often abbreviated GOPTS or GPTMS, is an epoxy-functional silane coupling agent that, like other silanes, bridges the inorganic and organic worlds. Its trimethoxysilyl end bonds to inorganic surfaces such as glass, silica, and metal oxides, while its epoxide (glycidyl) end reacts with resins, polymers, and biomolecules. This dual reactivity makes it a go-to reagent for adhesion promotion, surface modification, and molecule immobilization.
- How the two reactive ends are used: After the silane end is anchored to a surface through hydrolysis and condensation, the exposed epoxide group readily reacts with amines, hydroxyls, and other nucleophiles. That lets chemists covalently link a silanized surface to a coating resin, a polymer network, or a biomolecule such as a protein or nucleic acid. The result is a durable chemical bond rather than a merely physical one, which is why GOPTS is common in functional coatings and in diagnostic and materials research surfaces.
- Verified identity and purity: This TCI product (catalog G0210) is a minimum 97.0% (GC) grade with CAS number 2530-83-8. It is a colorless to almost colorless clear liquid, also known as glycidyl 3-trimethoxysilylpropyl ether. Confirming the CAS number and purity before use is worthwhile, since coupling and immobilization results depend on starting from a well-defined, high-quality reagent that behaves consistently from batch to batch.
- Storage and safe handling: As an alkoxysilane, GOPTS reacts with moisture, so containers should be kept tightly closed and protected from humidity to prevent premature hydrolysis that would reduce coupling performance. It should be handled with appropriate protective equipment, and the Safety Data Sheet reviewed before use. The product carries a California Prop 65 warning. Following the manufacturer's storage guidance preserves the reagent's reactivity for demanding surface and adhesion work.
Recommended For
- Coupling resins to glass, silica, and metal oxides
- Surface modification and adhesion promotion
- Biomolecule immobilization chemistry
- Research and industrial silane applications
Product Details
- Chemical name: 3-Glycidyloxypropyltrimethoxysilane (GOPTS)
- Purity: Min. 97.0% (GC)
- CAS number: 2530-83-8
- Physical state / color: Liquid / colorless to almost colorless
- Condition to avoid: Moisture sensitive
- Manufacturer: TCI (catalog G0210)
Available Variants
- G0210-25G — 3-Glycidyloxypropyltrimethoxysilane, 25 g
- G0210-100G — 3-Glycidyloxypropyltrimethoxysilane, 100 g
- G0210-500G — 3-Glycidyloxypropyltrimethoxysilane, 500 g
- The variants are the same reagent in 25 g, 100 g, and 500 g pack sizes; choose the quantity to match your usage.
Primary Industries
- Adhesives, coatings, and composites
- Materials science and surface chemistry
- Life science and diagnostics
- Research laboratories
Standards and Certifications
- California Prop 65 warning applies



