{"product_id":"mannitol-acs-1lb","title":"Mannitol, USP Grade, 1 lb","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat it is.\u003c\/strong\u003e This mannitol is USP grade D-mannitol, a white crystalline sugar alcohol supplied in a 1 lb size. It is used as a laboratory reagent, a bulking agent in freeze-drying, a carbon source in microbiology media, and an excipient in formulation work.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat USP grade means.\u003c\/strong\u003e USP grade material meets the United States Pharmacopeia monograph for mannitol. The monograph sets a melting range of 164 to 169 °C, a specific rotation of +137 to +145 degrees under the USP method, a loss on drying of no more than 0.3%, and a test for reducing sugars.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical identity.\u003c\/strong\u003e D-mannitol (CAS 69-65-8, C6H14O6, 182.17 g\/mol) is a six-carbon sugar alcohol and an isomer of sorbitol. It has a density of about 1.49 g\/cm³ and dissolves in water to about 156 g per liter at 18 °C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNon-hygroscopic and stable.\u003c\/strong\u003e Unlike sorbitol, mannitol absorbs little moisture from the air. That stability is why it is widely used as a tablet diluent and as a bulking agent that gives freeze-dried products a firm, elegant cake.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicrobiology.\u003c\/strong\u003e Mannitol is the fermentable carbohydrate in mannitol salt agar, where organisms that ferment it, such as Staphylococcus aureus, produce acid that changes the medium's phenol red indicator to yellow.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnalytical chemistry.\u003c\/strong\u003e Mannitol is also used in the laboratory to complex boric acid, which turns the weak acid into a stronger acid that can be titrated sharply with sodium hydroxide.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot for clinical use.\u003c\/strong\u003e This product is supplied for laboratory and manufacturing use. Mannitol injections used in medicine are separate, sterile products made under drug manufacturing controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePreparing solutions.\u003c\/strong\u003e Mannitol dissolves readily in warm water. For concentrated solutions, warm gently with stirring and allow the solution to cool, watching for crystallization at high concentrations, since mannitol solubility falls as temperature drops.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling at a glance.\u003c\/strong\u003e Mannitol has low toxicity and is not generally classified as hazardous. Avoid creating dust, wear safety glasses and gloves as standard practice, and keep the container closed in a dry place.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eTechnical Specifications\u003c\/h4\u003e\n\u003ctable style=\"width:100%; border-collapse:collapse; border:1px solid #cfcfcf; margin-bottom:28px;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eD-Mannitol\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e69-65-8\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eEC Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e200-711-8\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eMannitol, mannite, (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eFormula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eC6H14O6\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e182.17 g\/mol\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eGrade\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eUSP\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eMelting Range (USP)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e164 to 169 °C\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eSpecific Rotation (USP method)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e+137 to +145 degrees\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eLoss on Drying (USP)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.3% max (105 °C, 4 hours)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eReducing Sugars\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eMeets USP test\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eDensity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eAbout 1.49 g\/cm³\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eWater Solubility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eAbout 156 g\/L (18 °C)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eAppearance\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eWhite crystalline powder\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eHazard Profile\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eNot classified as hazardous (confirm on SDS)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003ePackage Size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e1 lb\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eApplications \/ Common Uses\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFreeze-drying:\u003c\/strong\u003e Serves as a bulking agent for lyophilized formulations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicrobiology media:\u003c\/strong\u003e Provides fermentable carbohydrate in mannitol salt agar.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoric acid titration:\u003c\/strong\u003e Complexes boric acid for sharp titration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation work:\u003c\/strong\u003e Acts as a non-hygroscopic diluent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTeaching labs:\u003c\/strong\u003e Demonstrates sugar alcohol chemistry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage, Handling \u0026amp; Shipping\u003c\/h4\u003e\n\u003cp\u003eStore tightly closed in a cool, dry place at room temperature, away from strong oxidizers. Mannitol is stable and absorbs little moisture, but keeping it sealed preserves its USP quality.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncompatible materials:\u003c\/strong\u003e Strong oxidizers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePersonal protection:\u003c\/strong\u003e Safety glasses, gloves, and dust control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpill response:\u003c\/strong\u003e Sweep up without raising dust and place in a closed container.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFirst aid:\u003c\/strong\u003e Eyes: rinse with water if irritation occurs.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eRelated Categories \u0026amp; Services\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eShop \u003ca href=\"https:\/\/labproinc.com\/collections\/organic-compounds\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eOrganic Compounds\u003c\/a\u003e for related products in this category.\u003c\/li\u003e\n\u003cli\u003eExplore \u003ca href=\"https:\/\/labproinc.com\/collections\/general-chemistry\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eGeneral Chemistry\u003c\/a\u003e and \u003ca href=\"https:\/\/labproinc.com\/collections\/acs-grade-laboratory-chemicals\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eACS Grade Laboratory Chemicals\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/labproinc.com\/pages\/be-a-lab-pro-vmi-program\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eVendor Managed Inventory (VMI) Program\u003c\/a\u003e: Lab Pro can stock, track, and replenish this item on site so it never runs out. Contact info@labproinc.com or 888-452-2776 to set up a VMI assessment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eRelated Articles\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/news\/chemical-dilution-calculator\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eChemical Dilution Calculator: Acid \u0026amp; Solvent Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/chemicals-and-solvents\/the-importance-of-deionized-water-in-laboratory-applications\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eThe Importance of Deionized Water in Laboratory Applications\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/chemicals-and-solvents\/mastering-ph-control-unveiling-the-secrets-of-effective-ph-buffer-solutions\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eMastering pH Control: Unveiling the Secrets of Effective pH Buffer Solutions\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Lab Pro Inc","offers":[{"title":"Default Title","offer_id":47261545136277,"sku":"ZM0215-450","price":145.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0757\/2327\/6437\/files\/MainImage_0e2210ce-7de5-4772-8f1a-d58acd72ab4c.png?v=1791931218","url":"https:\/\/checkout.labproinc.com\/products\/mannitol-acs-1lb","provider":"Lab Pro Inc Plus","version":"1.0","type":"link"}