{"product_id":"urea-acs-1lb-zu0065-450","title":"Urea, ACS Grade, 1 lb","description":"\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat it is.\u003c\/strong\u003e This urea is supplied as ACS reagent-grade white crystals in a 1 lb size. This high-purity organic compound is used as a protein denaturant, nitrogen source, and reagent in biochemistry, analytical chemistry, and teaching labs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWhat ACS grade guarantees.\u003c\/strong\u003e ACS reagent urea assays at 99.0 to 100.5%, melts at 132 to 135 °C, and limits insoluble matter and sulfated ash to 0.01% each, iron and heavy metals to 0.001% each, chloride to 5 ppm, and sulfate to 0.001%.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChemical identity.\u003c\/strong\u003e Urea (carbamide, CAS 57-13-6, CH4N2O, 60.06 g\/mol) is the diamide of carbonic acid. It is highly soluble in water and was the first organic compound synthesized from inorganic starting materials in 1828.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein denaturant.\u003c\/strong\u003e Concentrated urea solutions, typically 6-8 M, unfold proteins by disrupting hydrogen bonds and hydrophobic interactions. Urea solubilizes inclusion bodies, denatures proteins for electrophoresis, and supports protein refolding studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNucleic acid work.\u003c\/strong\u003e Urea is a component of denaturing polyacrylamide gels for DNA and RNA electrophoresis, where it keeps nucleic acids single-stranded so they separate by length.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUse fresh solutions.\u003c\/strong\u003e Urea in solution slowly decomposes to ammonium cyanate, which can carbamylate proteins and alter their charge. Prepare urea solutions fresh, avoid heating them, and deionize stored solutions if you must keep them.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOther uses.\u003c\/strong\u003e Urea serves as a nitrogen standard and reagent in analytical chemistry, in fertilizer and feed research, as a moisturizer in cosmetics, in diesel exhaust fluid for emission control, and in teaching labs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePreparing urea solutions.\u003c\/strong\u003e Dissolving urea absorbs heat, so solutions cool noticeably as it dissolves. Allow them to return to room temperature before adjusting volume. Use high-purity water, and filter solutions for electrophoresis or chromatography.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHandling at a glance.\u003c\/strong\u003e Urea is low hazard, but dust may irritate the eyes and respiratory tract. Wear safety glasses and gloves, avoid creating dust, and keep the container tightly closed since urea absorbs moisture.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eTechnical Specifications\u003c\/h4\u003e\n\u003ctable style=\"width:100%; border-collapse:collapse; border:1px solid #cfcfcf; margin-bottom:28px;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eUrea\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e57-13-6\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eEC Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e200-315-5\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eCarbamide, carbonyl diamide\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eFormula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eCH4N2O (NH2CONH2)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e60.06 g\/mol\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eGrade\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eACS reagent\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eAssay\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e99.0 to 100.5%\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eMelting Range\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e132 to 135 °C\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eInsoluble Matter\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.01% max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eSulfated Ash \/ Residue after Ignition\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.01% max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eChloride (Cl)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e5 ppm max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eSulfate (SO4)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.001% max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eIron (Fe)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.001% max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eHeavy Metals (as Pb)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e0.001% max\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eWhite crystals\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eWater Solubility\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eHighly soluble\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eTypical Denaturing Concentration\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e6 to 8 M\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003eHazard Profile\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003eNot classified as hazardous (confirm on SDS)\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left; width:32%; background:#f5f5f5;\"\u003e\u003cstrong\u003ePackage Size\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"border:1px solid #cfcfcf; padding:8px 12px; vertical-align:top; text-align:left;\"\u003e\u003cstrong\u003e1 lb\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch4\u003eApplications \/ Common Uses\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtein denaturation:\u003c\/strong\u003e Unfolds proteins at 6 to 8 M.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDenaturing gels:\u003c\/strong\u003e Keeps DNA and RNA single-stranded.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInclusion body solubilization:\u003c\/strong\u003e Dissolves aggregated recombinant proteins.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnalytical reagent:\u003c\/strong\u003e Serves as a nitrogen standard and reagent.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTeaching labs:\u003c\/strong\u003e Demonstrates organic synthesis history and protein chemistry.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eStorage, Handling \u0026amp; Shipping\u003c\/h4\u003e\n\u003cp\u003eStore tightly closed in a cool, dry place at room temperature, away from strong oxidizers, nitrites, and hypochlorites. Urea absorbs moisture, so reseal the container promptly and prepare solutions fresh rather than storing them long term.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncompatible materials:\u003c\/strong\u003e Strong oxidizers, sodium hypochlorite, nitrites, and strong acids.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePersonal protection:\u003c\/strong\u003e Safety glasses, gloves, and dust control.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSpill response:\u003c\/strong\u003e Sweep up without raising dust and place in a closed container.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFirst aid:\u003c\/strong\u003e Eyes: rinse with water for several minutes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eRelated Categories \u0026amp; Services\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003eShop \u003ca href=\"https:\/\/labproinc.com\/collections\/acs-grade-laboratory-chemicals\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eACS Grade Laboratory Chemicals\u003c\/a\u003e for related products in this category.\u003c\/li\u003e\n\u003cli\u003eExplore \u003ca href=\"https:\/\/labproinc.com\/collections\/organic-compounds\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eOrganic Compounds\u003c\/a\u003e and \u003ca href=\"https:\/\/labproinc.com\/pages\/buffers-standards-solutions\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eBuffers, Standards \u0026amp; Solutions\u003c\/a\u003e.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/labproinc.com\/pages\/be-a-lab-pro-vmi-program\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eVendor Managed Inventory (VMI) Program\u003c\/a\u003e: Lab Pro can stock, track, and replenish this item on site so it never runs out. Contact info@labproinc.com or 888-452-2776 to set up a VMI assessment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eRelated Articles\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/news\/chemical-dilution-calculator\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eChemical Dilution Calculator: Acid \u0026amp; Solvent Guide\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/chemicals-and-solvents\/the-importance-of-deionized-water-in-laboratory-applications\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eThe Importance of Deionized Water in Laboratory Applications\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/labproinc.com\/blogs\/chemicals-and-solvents\/mastering-ph-control-unveiling-the-secrets-of-effective-ph-buffer-solutions\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eMastering pH Control: Unveiling the Secrets of Effective pH Buffer Solutions\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Lab Pro Inc","offers":[{"title":"Default Title","offer_id":47266340339861,"sku":"ZU0065-450","price":77.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0757\/2327\/6437\/files\/Main_Image_140e795a-00bd-4806-9ffd-d5a6363f1aec.png?v=1791930561","url":"https:\/\/checkout.labproinc.com\/products\/urea-acs-1lb-zu0065-450","provider":"Lab Pro Inc Plus","version":"1.0","type":"link"}